Psoriasis is an abnormal skin disorder that often manifests as scaly patches that are typically red and itchy. It is considered an autoimmune disorder and it occurs more often in men than in women, according to a new study conducted by researchers at Umeå University and Karolinska Institutet.
Published in the American Journal of Clinical Dermatology, Swedish researchers studied 5,438 men and women with psoriasis who were native to Sweden and learned that women had a statistically lower incidence of severe psoriasis than men. This is surprising, considering that autoimmune disorders tend to favor females more than males. Other autoimmune disorders such as systemic lupus erythematosus (SLE), multiple sclerosis (MS), and rheumatoid arthritis (RA) are all more prevalent in women than they are in men.
“Our results tell us that the well-established gender differences in the utilization of psoriasis care can at least partially be explained by a higher prevalence of more severe disease in men,” says Marcus Schmitt-Egenolf, who is a researcher at the Department of Public Health and Clinical Medicine at Umeå University and senior author of the study.
This conclusion was made using PsoReg: a detailed disease measurement data resource of all patients measured with the standard Psoriasis Area Severity Index (PASI). The analysis found that women had significantly (P<0.001) lower median PASI values when compared to men (5.4 for women/7.3 for men). The findings of severe psoriasis in men were consistent across all ages and in all areas of the body, with the exception of the head.