Catalyst Pharma’s Firdapse shows treatment effect in certain patients with myasthenia gravis; shares jump 14%

Amifampridine enhances neuromuscular transmission by blocking the potassium channel. This causes depolarization of the presynaptic membranes which opens the calcium channel thereby enabling muscle fibers to contract.

MG is an autoimmune neuromuscular disorder characterized by varying degrees of weakness of the skeletal muscles.

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