Depression or anxiety disorders can indicate thyroid disease, although these symptoms are typically not enough on their own to warrant a diagnosis. These psychiatric symptoms and mood disturbances may present in a generalized or acute manner. In other words, patients may slowly sink into sustained periods of mild to severe depression, or they could experience unexpected, sudden and intense outbursts of symptoms, such as panic attacks.
Mood imbalances are more often seen with underactive thyroids. These symptoms may be accompanied by a general feeling of malaise or lethargy, an inability or lack of desire to concentrate, or a feeling of mental sluggishness.