How Does Gastric Bypass Surgery Cure Type 2 Diabetes?

“With more research, we hope that we can find ways to, as we say, bypass the bypass,” Stylopoulos said. “This mechanism we found is very promising because unlike other organs, such as the brain for example, intestines are easily accessible, and the life of those cells is only about two days, so we can easily study and manipulate these cells without having long-term problems.”

Charles Mobbs, a professor of neuroscience, endocrinology, and geriatrics at the Icahn School of Medicine at Mount Sinai Medical Center in New York, told Healthline the new study may make the medical community more willing to approve gastric bypass surgery to treat diabetes, independent of a patient’s body weight. He said more research is needed, however, to figure out why gastric bypass surgery causes the small intestine to make GLUT-1.

“It may be possible to pharmacologically mimic the effect of the undigested food to induce glucose metabolism in the intestine (which of course is highly accessible to oral drugs) independent of surgery,” Mobbs said. “This could lead to a revolution in the treatment of diabetes, possibly including type 1 as well as type 2.”