Similar post-disease symptoms can occur after other kinds of conditions caused by bacterial infections, including Guillain-Barre syndrome and Reiter’s syndrome. There is a controversy, however, over PTLDS. Some doctors believe that chronic Lyme disease symptoms are caused by a persistent Lyme disease infection. Others think they’re caused by damage to the body during infection. Because the tests used to check for Lyme disease are still evolving, it’s not known which group is correct.
Some doctors treat PTLDS with long-term courses of antibiotics. However, studies suggest no real benefits to taking antibiotics over long periods. It could even be harmful.
According to the CDC, the best treatment plans for people with PTLDS are similar to those used to treat patients with fibromyalgia or chronic fatigue syndrome. This may include taking medications for pain and fatigue, talk therapy, and stress-reduction techniques such as deep breathing or yoga.