JAK Inhibitors Show Promise for Alopecia, Eczema, Vitiligo

Rapid Repigmentation in Vitiligo

A case study of a woman in her 50s with widespread vitiligo was coauthored by Dr King.

Oral tofacitinib 5 mg every other day was initiated. After 3 weeks, the dosage was increased to 5 mg daily. After 2 months, “partial repigmentation of the face and upper extremities was evident,” Dr King and his coauthor write. And after 5 months, “repigmentation of the forehead and hands was nearly complete.”

“The fairly rapid response and the repigmentation of the hands, which are often resistant to therapy, are noteworthy,” the pair writes.

And the case of a patient with vitiligo and alopecia treated with oral ruxolitinib who experienced rapid repigmentation was recently described

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