Protein Triggers Immune Response in Lupus Patients

Scientists at the University of Vermont’s Larner College of Medicine discovered that a mitochondria protein, called mitochondrial antiviral-signaling protein (MAVS), can trigger type I IFN production in SLE patients with no signs of viral infection.

“Typically, this protein — mitochondrial antiviral signaling or MAVS — is responsible for recognizing viral infections,” Dr. Iwona A. Buskiewicz, the study’s first author, said in a press release. Her team’s study is “the first paper showing that the interferon pathway can be activated by something other than viral infection or nucleic acids,” she said.

Mitochondria are small organelles within our cells commonly known as the cells’ powerhouses, or energy producers.

Next Page

Leave a Reply

Your email address will not be published. Required fields are marked *