Lupus and Kidney Disease (Lupus Nephritis)

A dietitian talking to a patient about healthy food.

What are the complications of lupus nephritis?

Treatment works well to control lupus nephritis, so you may not have complications.

Between 10 to 30 percent of people who have lupus nephritis develop kidney failure.6 Learn more about what happens if your kidneys fail.

The most severe form of lupus nephritis, called diffuse proliferative nephritis, can cause scars to form in the kidneys. Scars are permanent, and kidney function often declines as more scars form. Early diagnosis and treatment may help prevent long-lasting damage.

People who have lupus nephritis are at a high risk for cancer, primarily B-cell lymphoma —a type of cancer that begins in the cells of the immune system. They are also at a high risk for heart and blood vessel problems.

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