How Is Down Syndrome Inherited?

Chances of Giving Birth to a Child with Down Syndrome

Now you have some understanding of “How is Down syndrome inherited?” you may also be interested in the chances of giving birth to a child with this condition. The condition affects people in all parts of the world irrespective of their economic levels or races. However, it is more common in women who conceive later in their lives. There is a one in 350 chance of giving birth to a child with Down syndrome when a woman becomes pregnant at the age of 35. The chance goes up to 1 in 100 for women becoming pregnant at age 40. At age 45, it is more likely to give birth to a child with Down syndrome because the incidence becomes 1 in 30.

What about the Second Baby?

If one of your babies has Down syndrome, there will be 1 in 100 chances that you will have another child with trisomy 21. In case the father is the carrier, there is a 3% risk of recurrence of translocation. The risk increases to 10-15% in case the mother already has it. Genetic counseling helps in this regard and plays a role in identifying the origin of translocation.

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