Multiple Sclerosis Prognosis Snapshot
- Being older than age 40 at the onset of symptoms;
- Having more than two attacks in the first two years after onset;
- Having symptoms that affect urinary control, mobility, or mental functioning at disease onset, or having initial symptoms in many different areas of the body;
- Showing a high frequency of relapses, since repeat early relapses can cause the disease to progress quickly;
- Showing a high number of brain or brainstem lesions in an MRI scan at the time of diagnosis, or showing new or gadolinium-enhancing lesions in an MRI, implying active inflammation;
- Scoring more than 1.5 on the Expanded Disability Status Scale (EDSS, a scale that quantifies disability) after a second attack.