3. Pancreatic cancer
Pancreatic cancer or pancreatic carcinoma is listed third among the most painful diseases. It is one of the most common cancers diagnosed in people. It is generally caused in people with diabetes, having chronic pancreatitis or due to excessive smoking. Pancreas is considered as both exocrine and endocrine gland but it affects any one part of it. It is found to run in family rarely. The risk of getting such cancer increases with an increase in age.
2. Dercum’s disease (adipose dolorosa)
Scientific name of the Dercum’s disease is Adipose Dolorosa. This disease has no known cause till date. It is said to be an auto immune disease .One of the most painful diseases in the world. Some people mistake it with obesity. But it is much worse than that. In this condition, fatty lumps form in parts of the body causing extensive pain. Full treatment is not possible, though medicine is given to ease the pain than to remove the adipose. Sometimes it is known to run in families.