1. Fothergill’s disease (trigeminal neuralgia):
A disease which tops the list of world’s painful diseases. Such painful disease and cause still unknown. Scientifically known as Trigeminal Neuralgia. This disease affects areas of face. It causes intense pain in the facial area. The disease is also quoted as suicide disease sometimes. The symptoms include pain in the face. This is a kind of neural disorder. Mouth being a sensitive area, it causes immense problems in activities like eating, brushing etc. Even touching can cause an unbearable pain to the patient.