Doctor Jack Kruse’s Recommendations for Diabetic Peripheral Neuropathy
Dr. Jack Kruse is a neurosurgeon and self-described “Optimal Health Educator.” He makes some important scientific observations about diabetic peripheral neuropathy in his excellent essay “What to Do About Neuropathy.”
In this essay, Dr. Kruse talks about the role of blue light and extreme low frequency (ELF) magnetic fields. He also discusses the critical role sufficient dietary iodine plays for proper ketogenesis in our nerves, which he explains is critical for myelination of all nerves in humans. (Note: myelination is the creation of a protective insulating layer around nerves.)
Dr. Kruse advises his patients to avoid non-native EMF from cell phones and from any blue light emitting diode in their environment. He also recommends avoiding sugar alcohols found in many low carb foods, as well as the sweetener sorbitol like the plague.
Other recommendations for DPN by Dr. Kruse include:
- A strict low carb, paleo type ketogenic diet, especially like the one in Dr. Kruse’s book “Epi-paleo Rx: The Prescription for Disease Reversal and Optimal Health.”
- Be very careful of frying any carbohydrates. Carbohydrates subjected to frying in PUFA oils form the chemical acrylamide, a compound which is strongly linked to the development of peripheral neuropathy.
- Use of iodine and iodide supplements, R-alpha lipoic acid, resveratrol, PQQ, magnesium, and CoEnzyme Q10 to decrease cellular stress. (Note: R-alpha lipoic acid is a “carnitine like” analog which is thought to balance carnitine depletion and is often used as a treatment of diabetic peripheral neuropathy.)
- Fatty acid balance to reduce peroxide generation. The goal, Dr. Kruse says, is to decrease omega-6 fats and increase omega-3 fats, as well as increase gamma linolenic acid (GLA). Borage oil has copious amounts of GLA, as does black currant oil and evening primrose oil. These oils can help increase blood flow to decrease cellular stress.
- Very liberal replacement of B complex vitamins, especially B1 and B12.
- Optimization of vitamin D3 and vitamin E levels because of their immune modulating and antioxidant effects in nerves. Use of inositol is also a treatment option.
- Zinc, magnesium, and vitamin K2 replacement/supplementation. Zinc and magnesium are two of the most common mineral deficiencies in neuropathic pain. Zinc aids tremendously in wound healing.
- Supplementation with N-Acetyl Cysteine (NAC) and Acetyl-L-Carnitine. NAC is a precursor for the essential compound glutathione, which helps rid the nerve of the free radicals produced by the polyol pathway. Carnitine is replaced because polyol pathway depletes it.
- Optimization of thyroid hormone function is critical.
Two other supplements to strongly consider are Myo-Inositol and D-Chiro-Inositol, which are two substances that belong to the B-vitamin complex and which are produced in the body. Studies, as well as anecdotal evidence, have shown that a good combination is 2,000mg of Myo-Inositol and 50mg D-Chiro-Inositol.
Other supplements worth consideration are: cinnamon/cinnamon extract, soluble fibers, ashwagandha and other Ayurvedic herbs, and GTF chromium.